Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs.

Looking for a best bet for Sunday’s NFL action? You’ve come to the right place, as the SI Betting team has been making ...

49ers 24, Texans 16: San Francisco may be without defensive pillars Nick Bosa and Fred Warner, but the Houston offense has ...

Mike Florio and Chris Simms preview an inter-conference matchup between the San Francisco 49ers and the Houston Texans, ...

Get a prediction, pick and odds for the NFL Week 8 matchup between the Houston Texans and the San Francisco 49ers.

McCaffrey shattered records with a 200-yard game, showcasing his dual-threat dominance and historic receiving consistency. He ...

USA Today's NFL experts make their picks for a Week 8 showdown between the Houston Texans and San Francisco 49ers ...

On "49ers Talk," Jennifer Lee Chan and Matt Maiocco discuss Robert Saleh’s candidacy for vacant NFL head coaching positions ...

One reason the 49ers didn't get flagged is because pulling is a penalty that NFL officials almost never call. According to ...

To Nix’s credit, he did complete a couple of nice back-shoulder passes when the Giants finally decided to play tight man ...

The shorthanded San Francisco 49ers shocked the Atlanta Falcons in Week 7 NFL action on Sunday Night Football.

San Francisco 49ers’ Tatum Bethune (48) leaves the field after their 20-10 win over the Atlanta Falcons at Levi's Stadium in ...