Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs.

Looking for a best bet for Sunday’s NFL action? You’ve come to the right place, as the SI Betting team has been making ...

San Francisco's Christian McCaffrey and George Kittle pose challenges for Houston's defense, and 49ers' pass rush will be key ...

49ers 24, Texans 16: San Francisco may be without defensive pillars Nick Bosa and Fred Warner, but the Houston offense has ...

The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.

Meanwhile, the Texans haven't been as fortunate to begin the 2025 campaign. Houston has started 2-4 and is fresh off a 27-19 ...

Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a ...

Preview the Week 8 matchup between the Houston Texans and San Francisco 49ers with predictions, odds, over/under, spread, ...

The 49ers' top quarterback has missed five of seven games this season so far. Here's the latest on his status for Week 8.