A new system can dial expression of synthetic genes up or down

For decades, synthetic biologists have been developing gene circuits that can be transferred into cells for applications such ...

Rewriting the rules of genetics: Study reveals gene boundaries are dynamic, not fixed

Molecular biologists have long believed that the beginning of a gene launched the process of transcription—the process by ...
News-Medical.Net on MSN

SMOC1 gene plays a surprising role in the development of type 2 diabetes

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S., and ...
eLife

Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake

This important study uses innovative microfluidics-based single-cell imaging to monitor replicative lifespan, protein localization, and intracellular iron levels in aging yeast cells. The evidence for ...
EMBO Press

Type IV secretion systems: from structures to mechanisms

Conjugation is mediated by a large molecular machinery termed Type IV secretion system (T4SS), embedded within the donor cell ...