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Houston Texans, San Francisco 49ers

49ers vs. Texans picks: Who do experts predict will win Week 8 matchup?

After defeating the Atlanta Falcons 20-10 at Levi's Stadium last Sunday, the San Francisco 49ers are on the road again in Week 8 for an interconference battle with the Houston Texans at NRG Stadium.

· 3h · on MSN

3 Critical Matchups to Watch When the 49ers Face the Texans

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Texans vs. 49ers 2025 Prediction, Odds, Picks - Oct 26

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Texans vs. 49ers best bets, picks and odds | Week 8 2025

Check out best bets for when the Houston Texans (2-4) and the San Francisco 49ers (5-2) play at NRG Stadium on Sunday, October 26, 2025.

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Houston Texans vs. San Francisco 49ers: Fantasy football advice and predictions

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How to watch the 49ers vs. Texans on Sunday

49ers rule out Brock Purdy, Ricky Pearsall

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· 1d · on MSN

49ers rule out Brock Purdy, Ricky Pearsall for Texans game

With starter Brock Purdy slowly working his way back from the right big toe injury that's kept him out since Week 4, the 49ers will again turn to backup Mac Jones on Sunday against the Texans. Ricky Pearsall also is out.

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Mac Jones to start vs. Texans, Brock Purdy out again

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Brock Purdy Out for 49ers vs. Texans amid Turf Toe Injury, Mac Jones to Make 6th Start

13hon MSN

49ers vs. Texans: Where to watch NFL Week 8, betting odds, promos, score prediction for Mac Jones vs CJ Stroud

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. Before you make any Texans vs. 49ers picks, make sure to check out what the SportsLine Projection Model has to say.

Niners Wire

San Francisco 49ers vs. Houston Texans live stream, TV channel, start time, odds | Week 8 2025

Preview the San Francisco 49ers' NFL Week 8 matchup with the Texans, including live stream, TV channel, odds, and game information.

Click2Houston

How Texans’ defense approaches matchup with 49ers star Christian McCaffrey: ‘Hard to make 11 guys miss

He’s on pace to finish the season with 1,129 rushing yards and seven scores and 129 catches for 1,253 yards and seven touchdowns. He leads the NFL with 132 carries, rushing for 435 yards and three scores and has 53 catches for 516 yards and three touchdowns.

Texans Wire on MSN

Texans expected to be without WRs Nico Collins, Christian Kirk in Week 8 vs. 49ers

The Houston Texans look to right the offense on Sunday when they battle the San Francisco 49ers and they'll be doing so short-handed on offense.

Tennessee Titans vs. Indianapolis Colts injury report | Week 8 2025

Take a look at the injury report for the Tennessee Titans (1-6), which has 14 players listed (including Tony Pollard), as the Titans prepare for their matchup versus the Indianapolis Colts (6-1) at Lucas Oil Stadium,