Nature

Targeted rearrangement of a chromosomal repeat sequence by transfection of a homologous DNA sequence using purified integrase

Although several methods of manipulating chromosomal genes have been reported, no highly efficient site-specific integration or alteration of genes at a desired site has been achieved. The ...
JSTOR Daily

Netropsin, a Minor Groove Binding Ligand: A Potential Radioprotective Agent

Minimizing radiation-induced damages in DNA is an important aspect in the development of chemical radioprotectors. The aim of this study was to evaluate the possible radioprotective ability of the DNA ...
JSTOR Daily

Fertility Repression of F-Like Conjugative Plasmids: Physical Mapping of the R6-5 finO and finP Cistrons and Identification of the finO Protein

The locations of the fertility inhibition genes finO and finP of the F-like conjugative multiple antibiotic-resistance plasmid R6-5 have been determined. As found previously for that of the fertility ...
Nature

Piperonal ciprofloxacin hydrazone induces growth arrest and apoptosis of human hepatocarcinoma SMMC-7721 cells

To investigate the cytotoxic effects of piperonal ciprofloxacin hydrazone (QNT4), a novel antibacterial fluoroquinolone derivative, against human hepatocarcinoma SMMC-7721 cells. Human hepatocarcinoma ...