McArdle's disease, also known as Glycogen Storage Disease Type V, or GSD5, is a congenital disorder of muscle metabolism. It occurs when the body loses its ability to break down glycogen leading to ...

McArdle disease, also known as glycogen storage disease type V, is an inherited metabolic disorder marked by a deficiency of myophosphorylase, the enzyme essential for the breakdown of glycogen in ...

IN 1951 McArdle 1 described a patient with a hitherto unrecognized muscle disorder in which marked weakness, cramping pain and prolonged stiffness of muscles were produced by moderate degrees of ...

This paper describes the cardiovascular, respiratory and metabolic responses to exercise in a patient with McArdle's syndrome and studies of the mechanisms involved. In particular we have been ...