“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

Molecular biologists have long believed that the beginning of a gene launched the process of transcription—the process by which a segment of DNA is copied into RNA and then RNA helps make the proteins ...

RNA-binding proteins (RBPs) are central regulators of post-transcriptional gene expression. They modulate key aspects of mRNA metabolism—such as splicing, ...

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D ...

Institute researchers have developed a new multi-omics method enabling the profiling of multiple histone modifications and ...

Elderberry juice intake triggers metabolic gene expression changes, enhancing glucose control and fat oxidation in overweight ...

Scientists have pinpointed specific neurons and microglia, crucial for emotion and inflammation, as key players in depression ...

Stanford study finds rapid brain cell evolution boosted human cognition but lowered autism gene activity, raising ...