The DNA in the cell nuclei of higher organisms is tightly coiled around protein complexes called nucleosomes, which repress gene expression. Researchers in Germany have now developed a model that ...

Eukaryotic genome stability relies on the presence of telomeres, specialized protein–DNA complexes that compose the very ends of the linear chromosomes 1. Telomeres form protective caps at the ends of ...

Scientists have created an unprecedented 3-dimensional structural model of a key molecular "machine" known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and ...

Scientists have created an unprecedented 3-dimensional structural model of a key molecular 'machine' known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and ...

In both physics and chemistry, the mesoscopic scale refers to the length scale on which the properties of a material or phenomenon can be studied, without entering into a discussion about the behavior ...

Erwin Chargaff's groundbreaking research, which showed that DNA base pairs had a complementary relationship, laid the foundation for James Watson's and Francis Crick's DNA model. When word spread that ...

UC Davis researchers have confirmed a central idea about chromosome repair, more than a quarter century after it was first proposed. The finding is important to scientists who seek to understand DNA ...