They will head out on the road to face off against the Arizona Cardinals at 4:05 p.m. ET at State Farm Stadium. The 49ers will be looking to extend their current five-game winning streak. Last Sunday,

The Arizona Cardinals are in a foul mood as they take a break from the NFL grind, mired in a frustrating five-game losing streak that has raised some uncomfortable questions about the direction of the franchise.

We’ve made it to another action-packed NFL Sunday, and the schedule is the lightest it will be all season long, but there are still plenty of exciting games throughout the day as Week 8 kicks into full swing.

The Arizona Cardinals and Indianapolis Colts play on Oct. 12, in a game on the NFL Week 6 schedule. Here's a look at the time, TV channel and broadcast information for the Week 6 NFL game, which will be played at the Colts' Lucas Oil Stadium. The Colts are ...

The Arizona Cardinals have had no shortage of issues this season, starting 2-5 despite lofty expectations. The question: Can their issues be solved?

The toll of losing quickly adds up in the NFL - and the Cardinals have endured quite the suffering stretch of football after their 2-0 start. Arizona is just the second team in NFL history to have lost five games in a row by a combined 13 points.

Against the Cardinals, Parsons played on 54 defensive snaps. Altogether, he came away with five tackles as well as three sacks, a career best. Additionally, Parsons was able to finish with four tackles for a loss and five quarterback hits. As a result, Parsons was named the NFC Defensive Player of the Week.

With Kyler Murray missing a second straight day of practice with a foot issue, there’s a real chance Jacoby Brissett could start for the Cardinals.