Take a look at the injury report for the San Francisco 49ers (5-2), which has 16 players listed (including Christian McCaffrey), as the 49ers prepare for their matchup versus the Houston Texans (2-4) at NRG Stadium, on Sunday, Oct. 26 at 1 p.m. ET.

49ers 24, Texans 16: San Francisco may be without defensive pillars Nick Bosa and Fred Warner, but the Houston offense has given no reason to believe it can be effective. The Texans' defense will keep them in this game for a bit but it can only do so much, as we saw Monday in Seattle.

San Francisco's Christian McCaffrey and George Kittle pose challenges for Houston's defense, and 49ers' pass rush will be key.

Preview the Week 8 matchup between the Houston Texans and San Francisco 49ers with predictions, odds, over/under, spread, betting lines and more.

Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a typical 2-4 losing team. They boast o

The Houston Texans look to right the offense on Sunday when they battle the San Francisco 49ers and they'll be doing so short-handed on offense.

Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the Rams. A big reason is the play of Jones under center. The veteran has resurrected his career in leading San Francisco forward despite injuries to a laundry list of players including Brock Purdy, Brandon Aiyuk, and Nick Bosa.

A week after the San Francisco 49ers improbably dominated the NFL's second-ranked offense, they'll be given a far less formidable test when they visit the Houston Texans.